| ncRNA name | hsa-let-7b-5p |
| ncRNA Category | miRNA |
| Disease name | age-related macular degeneration (AMD) |
| Species | Homo sapiens |
| Tissues/Cell_line | retinas |
| Methods | RNA-seq, immunoprecipitation, reporter assay, qPCR |
| Expression pattern | up-regulated |
| Functional description | Four of 12 miRNAs significantly elevated in AAMD retina (hsa-miR-155-5p, hsa-let-7a-5p, hsa-let-7b-5p hsa-let-7d-5p) also showed strong pairing capacity with miRNA target transcripts encoded by AAMD-associated SNPs resident in HLA-DQB1 (rs1063355, hsa-miR-155-5p) and TGFBR1 (rs868, hsa-let-7). |
| PubMed ID | 28343170 |
| Year | 2017 |
| Title | miRNAs, single nucleotide polymorphisms (SNPs) and age-related macular degeneration (AMD). |
| Drug-related ncRNA | NO |
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